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Angiogenesi e linfangiogenesi nel carcinoma ovarico by Laurențiu Pirtea, Andreea Adriana Jitariu, Marius Raica

Angiogenesi e linfangiogenesi nel carcinoma ovarico

by Laurențiu Pirtea , Andreea Adriana Jitariu , Marius Raica
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Book cover type: Paperback
  • ISBN13: 9786206732655
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 38.19
  • Language: Italian
  • Edition: N/A
  • Item Weight: 109 grams
  • BISAC Subject(s): General

Il cancro � attualmente la patologia pi� diffusa nell'uomo e negli ultimi due anni ha superato le malattie cardiovascolari in termini di incidenza specifica e mortalit�. Il carcinoma ovarico � noto da molto tempo per la sua imprevedibilit� in termini di evoluzione naturale. Esistono modelli di progressione e metastasi "standard" praticamente sconosciuti, nonch� una risposta differenziale e spesso incoerente alla terapia antitumorale adiuvante. Queste incertezze possono essere spiegate dalla conoscenza insufficiente dell'espressione del fattore di crescita cellulare, del microambiente tumorale e, forse non da ultimo, dell'angiogenesi e della linfangiogenesi, che sono state studiate molto meno nell'ovaio normale e nei tumori ovarici rispetto ad altre sedi tumorali. Nel presente studio abbiamo cercato di studiare gli aspetti dell'angiogenesi e della linfangiogenesi tumorale, nella speranza di riuscire a specificarne il valore prognostico e caratterizzare una serie di nuovi potenziali bersagli terapeutici. Questo lavoro non avrebbe potuto essere realizzato senza la collaborazione tra i Dipartimenti di Istologia e Ginecologia dell'Universit� "Victor Babeș" di Timișoara, e per questo ringrazio i colleghi di entrambi i dipartimenti.

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