Avanços actuais em Bacillus thuringiensis
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O Bacillus thuringiensis (B.t.) � uma bact�ria gram-positiva do solo utilizada como um dos entomopatog�nios para controlar as pragas de lepid�pteros no campo, bem como as pragas das culturas hort�colas. As v�rias formula��es de B.t. foram utilizadas com sucesso para proteger o ambiente e os alimentos da contamina��o de res�duos de pesticidas qu�micos na gest�o de pragas. A descoberta de toxinas de B.t. com uma nova atividade inseticida contra pragas e o desenvolvimento de plantas geneticamente modificadas abriram uma nova era de gest�o de pragas. As culturas transg�nicas de B.t., incluindo o milho, o algod�o e a soja, foram agora produzidas e comercializadas para proteger as culturas contra cerca de 30 das principais pragas de cole�pteros e lepid�pteros, beneficiando grandemente o ambiente e a economia. No entanto, com o cultivo a longo prazo de culturas B.t., algumas pragas-alvo desenvolveram gradualmente resist�ncia. Numerosos estudos indicaram que as muta��es nos genes de ativa��o de toxinas, de liga��o a toxinas e de imuniza��o de insectos s�o fontes importantes de resist�ncia � B.t.. Uma explora��o aprofundada dos mecanismos de resist�ncia B.t. correspondentes ajudar� na conce��o de novas estrat�gias de preven��o e gest�o de pragas.
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