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Bialaczka - badanie molekularne i immunogenetyczne by Al-Marzoqi, Ali H.

Bialaczka - badanie molekularne i immunogenetyczne

by Ali H. Al-Marzoqi , Zainab W. Maroof , Israa H. Al-Hussaini
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Book cover type: Paperback
  • ISBN13: 9786202498746
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Wydawnictwo Nasza Wiedza
  • Publisher Imprint: Wydawnictwo Nasza Wiedza
  • Publication Date:
  • Pages: 104
  • Original Price: GBP 28.62
  • Language: Polish
  • Edition: N/A
  • Item Weight: 150 grams
  • BISAC Subject(s): General

Bialaczka charakteryzuje się występowaniem pojedynczych kom�rek krwiotw�rczych w ukladzie krążenia lub limfie. Niewylączne kom�rki (hematopoetyczne mikroorganizmy zalożycielskie) w pelni rozwinęly się w szpikowe lub limfoidalne kom�rki genealogiczne, z kt�rych wylaniają się wszystkie inne określone kom�rki. Jednym z gl�wnych zaburzeń ukladu krwiotw�rczego byla przewlekla bialaczka szpikowa (CML), kt�ra jest chorobą kom�rek macierzystych powodującą zaniechanie produkcji bialych krwinek. Konsekwencją, kt�ra powoduje CML jest translokacja chromosomalna proporcjonalna (wzajemna) między dwoma chromosomami; chromosomem {9}, gdzie znajduje się region kinazy Abelsona i chromosomem {22}, kt�ry zawiera region klastra punkt�w przerwania t(9;22). Chromosom Philedelphia (Ph) byl zjawiskiem powstalym w wyniku translokacji dla zregenerowanych 2 chromosom�w. Celem badania bylo zbadanie związku między zmianami jakościowymi konkurent�w a ryzykiem przewleklej bialaczki szpikowej poprzez: 1. Wykorzystanie tradycyjnej i RFLP PCR; 2. Badanie kilku rodzaj�w interleukin, kt�re są związane z CML; 3. Wykrywanie niekt�rych czynnik�w mikrobiologicznych WIRUSY.

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