• ISBN13: 9780521416986
• Binding: Hardcover
• Subject: Chemistry
• Publisher: Cambridge University Press
• Publisher Imprint: Cambridge University Press
• Publication Date: March 25, 1994
• Pages: 320
• Original Price: USD 135.0
• Language: English
• Edition: N/A
• Item Weight: 590 grams
• BISAC Subject(s): Physiology

This book describes the role of the neutrophil in infection and inflammation and provides an up-to-date review of the biochemistry and physiology of this cell, highlighting the mechanisms by which they seek out and destroy pathogenic microorganisms. The development of these cells during haematopoiesis is described and the mechanisms that lead to the production of reactive oxidants and the intracellular signal transduction systems that lead to the cell's activation are reviewed. The book also discusses recent discoveries concerning the role of cytokines in the regulation of neutrophil function together with the importance of the neutrophil as a generator of inflammatory cytokines. Finally, there is a description of the biochemical defects that give rise to some of the neutrophil-associated human diseases.