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Brustkrebsassoziierte Immuninfiltrate by Muhammad Asif Qureshi, Bushra Sikandar, Talat Mirza

Brustkrebsassoziierte Immuninfiltrate

by Muhammad Asif Qureshi , Bushra Sikandar , Talat Mirza
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Book cover type: Paperback
  • ISBN13: 9786203859683
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Verlag Unser Wissen
  • Publisher Imprint: Verlag Unser Wissen
  • Publication Date:
  • Pages: 104
  • Original Price: GBP 52.98
  • Language: German
  • Edition: N/A
  • Item Weight: 150 grams
  • BISAC Subject(s): General

Brustkrebs k�nnte ein potenzielles Ziel f�r die Immuntherapie sein. Die genauen mechanistischen Zusammenh�nge zwischen Brustkrebs infiltrierenden Immunzellen (und der damit verbundenen Entz�ndung) und der Karzinogenese sind jedoch weitgehend ungekl�rt. Obwohl mehrere Forscher weltweit die mit Brustkrebs assoziierten Immunzelldichten untersuchen, ist es wichtig, die Immunzelldichten in unserer eigenen Population zu beschreiben/charakterisieren, da HLA-Polymorphismus zu einer unterschiedlichen Immunzusammensetzung der Tumormikroumgebung f�hren kann. Die in diesem Buch vorgestellten Daten beschreiben verschiedene Immunzelldichten in der Mikroumgebung von Brustkrebs. Diese Daten k�nnten genutzt werden, um die zugrunde liegenden Mechanismen der Brustkarzinogenese besser zu verstehen und neue therapeutische Ziele zu identifizieren. Auf der Grundlage der in diesem Buch vorgestellten Ergebnisse k�nnten weitere Experimente konzipiert werden, um die Rolle jedes einzelnen Immuninfiltrats besser zu verstehen. Zusammenfassend haben wir die Immunzelldichten in der Mikroumgebung von Brustkrebs bei pakistanischen Patientinnen charakterisiert. Dies k�nnte die Grundlage f�r weitere Experimente bilden, um Molek�le von diagnostischer, therapeutischer und prognostischer Bedeutung zu identifizieren.

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