Cellule Natural Killer e virus dell'epatite C

Name: Cellule Natural Killer e virus dell'epatite C
Brand: Edizioni Sapienza
SKU: 9786209625978
Price: 5127.0 INR
Availability: InStock

by Noha Mahana , Somaya El-Deeb , Mona Hassouna

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ISBN13: 9786209625978
Binding: Paperback
Subject: N/A
Publisher: Edizioni Sapienza
Publisher Imprint: Edizioni Sapienza
Publication Date: March 22, 2026
Pages: 88
Original Price: USD 57.0
Language: Italian
Edition: N/A
Item Weight: 127 grams
BISAC Subject(s): Life Sciences / Biology

About The Book

Si ritiene che l'immunit� innata contribuisca alla risposta virologica sostenuta (SVR) alla terapia con interferone-α/ribavirina pegilati (peg-IFN-/ribavirina). Le cellule natural killer (NK) sono implicate nella regolazione della risposta immunitaria protettiva nei pazienti con infezione cronica da HCV. Abbiamo cercato di studiare il livello dei sottogruppi NK nei pazienti egiziani con HCV cronico e di analizzare l'influenza della terapia con IFN su tale livello. Sono stati raccolti campioni da pazienti con infezione cronica (n = 37) al basale e da un sottogruppo prima e dopo 6 mesi di terapia con peg-IFN-/ribavirina. Le cellule NK sono state caratterizzate mediante citometria a flusso. Il numero di cellule CD3- CD56+ era significativamente inferiore nei pazienti con infezione cronica da HCV prima del trattamento rispetto ai controlli sani, ma � aumentato durante la terapia con IFN. Si � osservato un aumento significativo del numero di cellule CD16+ e CD3- CD56+ nei pazienti con risposta virologica sostenuta (SVR) durante la terapia rispetto ai pazienti non responder (NR). Nel contempo, le cellule CD56+ erano significativamente aumentate nei pazienti con infezione cronica da HCV prima del trattamento rispetto ai controlli sani e sono diminuite durante la terapia nei responder.

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