Células assassinas naturais e vírus da hepatite C

Name: Células assassinas naturais e vírus da hepatite C
Brand: Edicoes Nosso Conhecimento
SKU: 9786209785054
Price: 5127.0 INR
Availability: InStock

by Noha Mahana , Somaya El-Deeb , Mona Hassouna

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ISBN13: 9786209785054
Binding: Paperback
Subject: N/A
Publisher: Edicoes Nosso Conhecimento
Publisher Imprint: Edicoes Nosso Conhecimento
Publication Date: March 22, 2026
Pages: 88
Original Price: USD 57.0
Language: Portuguese
Edition: N/A
Item Weight: 127 grams
BISAC Subject(s): Life Sciences / Botany

About The Book

Acredita-se que a imunidade inata contribua para a resposta virol�gica sustentada (SVR) � terapia com interfer�o-α/ribavirina peguilados (peg-IFN-/ribavirina). As c�lulas natural killer (NK) est�o implicadas na regula��o de uma resposta imunit�ria protetora em pacientes com infec��o cr�nica pelo VHC. Procuramos investigar o n�vel de subconjuntos de NK entre pacientes eg�pcios com VHC cr�nico e analisar a influ�ncia da terapia com IFN nesse n�vel. Foram recolhidas amostras de pacientes com infec��o cr�nica (n = 37) no in�cio do estudo e de um subconjunto antes e ap�s 6 meses de terapia com peg-IFN-/ribavirina. As c�lulas NK foram caracterizadas por citometria de fluxo. O n�mero de c�lulas CD3- CD56+ foi significativamente menor em pacientes com infec��o cr�nica por HCV antes do tratamento em compara��o com controles saud�veis, mas aumentou durante a terapia com IFN. Houve um aumento significativo no n�mero de c�lulas CD16+ e CD3- CD56+ em pacientes com respostas virol�gicas sustentadas (SVR) durante a terapia em compara��o com pacientes n�o respondedores (NR). Enquanto isso, as c�lulas CD56+ aumentaram significativamente em pacientes com infec��o cr�nica por HCV antes do tratamento em compara��o com controles saud�veis e diminu�ram durante a terapia em respondedores.

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