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Chimica dei farmaci e innovazioni terapeutiche by Chafaa, Fouad

Chimica dei farmaci e innovazioni terapeutiche

by Fouad Chafaa
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Book cover type: Paperback
  • ISBN13: 9786202457279
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 52.98
  • Language: Italian
  • Edition: N/A
  • Item Weight: 109 grams
  • BISAC Subject(s): Chemistry / General

La chimica terapeutica � una disciplina essenziale all'interfaccia tra la chimica e le scienze biomediche. Svolge un ruolo centrale nella progettazione e nella comprensione del meccanismo d'azione, nonch� nello studio del destino dei farmaci nell'organismo. Consente un'analisi approfondita della struttura dei principi attivi, la previsione del loro metabolismo e la valutazione delle loro interazioni con bersagli biologici, come enzimi o recettori. La padronanza dei gruppi funzionali, dei meccanismi di reazione e delle propriet� fisico-chimiche delle molecole � essenziale per prevederne la reattivit�, la biodisponibilit� e l'efficacia terapeutica. Anche la stereochimica svolge un ruolo fondamentale, poich� l'attivit� biologica di un farmaco � spesso strettamente dipendente dalla sua configurazione spaziale. Un singolo cambiamento nella disposizione tridimensionale pu� trasformare una molecola attiva in un composto inattivo o addirittura tossico. La chimica terapeutica rappresenta quindi un vero e proprio ponte tra le basi teoriche della chimica e le sue applicazioni pratiche nel campo della salute. Rappresenta una base di conoscenza essenziale per qualsiasi approccio innovativo alla farmacologia, alla ricerca farmaceutica e allo sviluppo di nuove terapie.

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