• ISBN13: 9780824705435
• Binding: Hardcover
• Subject: Medical, Nursing and Health Sciences
• Publisher: T&F
• Publisher Imprint: Mar Dekker
• Publication Date: April 6, 2001
• Pages: 664
• Original Price: GBP 190.0
• Language: English
• Edition: N/A
• Item Weight: 1262 grams

About the Book Written by over 50 internationally distinguished experts, 30 more than the first edition, and contains nine new chapters <p/>Continuing in the esteemed tradition and heralded success of the first edition, Chronic Lymphoid Leukemias, Second Edition offers a full overview of chronic lymphocytic leukemia (CLL) from multiple perspectives-covering all major developments since the previous edition was published eight years ago. <p/>Chronicling the complete history and variations of CLL-type leukemia, the Second Edition<br><li>reviews the origin, nature, and molecular differences between B-CLL and T-CLL/PLL leukemias <br></li><li>analyzes core constituents of apoptosis and causes for dysregulation of programmed cell death (PCD) in B-CLL <br></li><li>examines recent research on the role cytokines and regulatory molecules may play in cross-cell communication <br></li><li>profiles commonly used vectors for somatic gene therapy, as well as the latest advances in genetic engineering and vector design and production <br></li><li>utilizes up-to-the-minute techniques such as fluorescence in-situ hybridization (FISH) and comparative genomic hybridization (CGH) to detect genetic abnormalities and aberrations <br></li><li>explores current measures of supportive care with splenectomy, cytokine proteins, and intravenous immunoglobulin applications <br></li><li>identifies how to manage infectious and psychiatric complications in patients with CLL <br></li><li>and much more <br>Provides contemporary results on the efficacy of nucleoside analog combinations such as ara-C with fludarabine and cladribine and on the emerging nucleosides nelarabine and clofarabine <p/>Copiously supplemented with over 2500 literature references-1000 more than the first edition-Chronic Lymphoid Leukemias, Second Edition fulfills the reference needs of oncologists, hematologists, immunologists, pathologists, infectious disease specialists, internists, molecular biologists, and medical school students in these disciplines.</li>