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Citogenetica dei tumori maligni ematologici by Sebaa, Amel

Citogenetica dei tumori maligni ematologici

by Amel Sebaa
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Book cover type: Paperback
  • ISBN13: 9786208903886
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 92
  • Original Price: GBP 52.98
  • Language: Italian
  • Edition: N/A
  • Item Weight: 137 grams
  • BISAC Subject(s): Life Sciences / Biology

Nelle neoplasie ematologiche si possono identificare molte anomalie cromosomiche, sia per numero che per struttura. Esse hanno la particolarit� di essere acquisite e di evolvere in modo clonale. Nei tumori solidi sono stati identificati diversi tipi di anomalie cromosomiche. Oltre ai dati citologici e istologici, l'identificazione di un'anomalia genetica � parte integrante del processo diagnostico delle neoplasie ematologiche e di alcuni tumori solidi. L'identificazione di queste anomalie svolge anche un ruolo nella stratificazione prognostica e nelle scelte terapeutiche e consente di valutare la malattia residua dopo il trattamento. Le anomalie cromosomiche rilevate nei tumori maligni ematologici sono acquisite (limitate al clone maligno), clonali, primarie o secondarie. Le anomalie citogenetiche primarie sono generalmente specifiche di un'entit� patologica, mentre le anomalie secondarie possono essere meno specifiche; queste ultime riflettono l'evoluzione del clone maligno e testimoniano la sua instabilit� genetica.

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