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Citogenética dos tumores hematológicos malignos by Sebaa, Amel

Citogenética dos tumores hematológicos malignos

by Amel Sebaa
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Book cover type: Paperback
  • ISBN13: 9786208903893
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edicoes Nosso Conhecimento
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Publication Date:
  • Pages: 92
  • Original Price: GBP 52.98
  • Language: Portuguese
  • Edition: N/A
  • Item Weight: 137 grams
  • BISAC Subject(s): Life Sciences / Biology

Nos tumores malignos hematol�gicos, podem ser identificadas muitas anomalias cromoss�micas, tanto em n�mero como em estrutura. Estas anomalias t�m a particularidade de serem adquiridas e de evolu�rem de forma clonal. Foram identificados v�rios tipos de anomalias cromoss�micas nos tumores s�lidos. Para al�m dos dados citol�gicos e histol�gicos, a identifica��o de uma anomalia gen�tica faz parte integrante do processo de diagn�stico das doen�as malignas hematol�gicas e de certos tumores s�lidos. A identifica��o destas anomalias tamb�m desempenha um papel na estratifica��o do progn�stico e nas escolhas terap�uticas, e permite avaliar a doen�a residual ap�s o tratamento. As anomalias cromoss�micas detectadas em tumores hematol�gicos malignos s�o adquiridas (restritas ao clone maligno), clonais, prim�rias ou secund�rias. As anomalias citogen�ticas prim�rias s�o geralmente espec�ficas de uma entidade patol�gica, enquanto as anomalias secund�rias podem ser menos espec�ficas; estas �ltimas reflectem a evolu��o do clone maligno e atestam a sua instabilidade gen�tica.

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