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Coadiuvanti per vaccini a base vegetale by Amit Gupta

Coadiuvanti per vaccini a base vegetale

by Amit Gupta
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Book cover type: Paperback
  • ISBN13: 9786208991227
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 31.23
  • Language: Italian
  • Edition: N/A
  • Item Weight: 109 grams
  • BISAC Subject(s): Pharmacology

I coadiuvanti di origine vegetale sono relativamente unici in quanto presentano poche di queste limitazioni e hanno il vantaggio di essere potenti induttori dell'immunit� sia cellulare che umorale, rendendoli adatti a un ampio spettro di vaccini profilattici e terapeutici.Titoli anticorpali elevati e una risposta relativamente uniforme possono spesso essere ottenuti con l'uso di coadiuvanti.Tuttavia, l'allume � stato utilizzato per lungo tempo come coadiuvante per i vaccini e presenta una mancanza di efficienza e durata dell'effetto o reazioni locali inaccettabili. Tuttavia, il suo uso come adiuvante per i vaccini presenta dei limiti nel sostenere la risposta mediata dalle cellule. Sebbene negli ultimi decenni siano stati proposti diversi adiuvanti, la maggior parte di essi non � stata approvata per l'uso umano, con limitazioni quali la mancanza di efficacia, la tossicit� locale o sistemica inaccettabile, la difficolt� di produzione, la scarsa stabilit� e i costi proibitivi. In questo libro viene descritto un candidato a base vegetale isolato da piante medicinali, che pu� essere considerato un migliore adiuvante vaccinale rispetto all'allume, per migliorare il tasso di sieroconversione e le citochine e la protezione indotta dopo la vaccinazione.

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