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Componentes bioativos de corais moles marinhos egípcios by Tarik Mohamed

Componentes bioativos de corais moles marinhos egípcios

by Tarik Mohamed , Mohamed Elamir Hegazy , Abdelaaty Shahat
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Book cover type: Paperback
  • ISBN13: 9786209263347
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edicoes Nosso Conhecimento
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Publication Date:
  • Pages: 140
  • Original Price: GBP 66.9
  • Language: Portuguese
  • Edition: N/A
  • Item Weight: 195 grams
  • BISAC Subject(s): Chemistry / General

Os produtos naturais t�m sido historicamente uma fonte rica de compostos l�deres para a descoberta de medicamentos. Embora tenha come�ado h� apenas cinquenta anos, a investiga��o de organismos marinhos com o objetivo de procurar novos compostos biologicamente ativos ganhou agora um papel reconhecido neste tipo de estudos. O meu trabalho de investiga��o, realizado no �mbito do programa do livro, tem-se centrado neste campo de investiga��o e, em particular, no isolamento e identifica��o de constituintes bioativos de corais moles marinhos eg�pcios. Esta investiga��o resultou no isolamento de seis novos compostos, pertencentes a diferentes classes estruturais, alguns dos quais possuindo uma interessante atividade anticancer�gena. As estruturas de todos os novos compostos foram elucidadas utilizando m�todos espectrosc�picos modernos, incluindo 1D, 2D NMR, raios X e FAB-MS. Parte um: Sarcophyton glaucum A an�lise qu�mica das fra��es menos polares do extrato org�nico obtido a partir do Sarcophyton glaucum proporcionou tr�s novos compostos (1-3). Parte dois: Sarcophyton Trocheliophorum. A investiga��o qu�mica do coral mole levou ao isolamento de seis cembranoides, dois dos quais s�o novos, Trochelioid A (1) e B (2), e um, 16-oxosarcophytonin E(3).

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