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Computer Techniques in Preclinical and Clinical Drug Development

by Robert C. Jackson
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Current price ₹13,533.00
Original price ₹22,554.00
Original price ₹22,554.00
Original price ₹22,554.00
(-40%)
₹13,533.00
Current price ₹13,533.00

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Book cover type: Hardcover
  • ISBN13: 9780849376825
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: CRC Press
  • Publisher Imprint: CRC Press
  • Publication Date:
  • Pages: 256
  • Original Price: GBP 180.0
  • Language: English
  • Edition: N/A
  • Item Weight: 536 grams
  • BISAC Subject(s): Chemistry / General

It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational methods to improve the success rate in drug development?" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

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