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Cupriavidus pauculus (ex-cdc group ivc-2) by Collectif

Cupriavidus pauculus (ex-cdc group ivc-2)

by Collectif
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Book cover type: Paperback
  • ISBN13: 9783841793973
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Univ Europeenne
  • Publisher Imprint: Univ Europeenne
  • Publication Date:
  • Pages: 116
  • Original Price: GBP 31.0
  • Language: French
  • Edition: N/A
  • Item Weight: 182 grams
  • BISAC Subject(s): Life Sciences / Microbiology

Notre étude de CDC group IVc-2 a débuté en 1995 lors de l'observation de cinq cas de septicémies à l'hôpital Trousseau (APHP, Paris). La génotypie par PCR aléatoire (RAPD) montrait un seul génotype. L'électrophorèse en champ pulsé, appliquée à nos isolats ainsi que ceux collectés dans divers hôpitaux franciliens, a échoué. Ces isolats étaient indifférenciés après génotypie par PCR-ribotypage, PCR-RFLP, IRS-PCR. La RAPD suffit pour différencier les souches provenant de collections, américaine (ATCC) et belge (LMG). Les gènes de l'ARNtAla et de l'ARNtIle sont présents dans l'espace 16S-23S. CDC Group IVc-2 a d'abord été nommé Ralstonia paucula puis Wautersia paucula et actuellement Cupriavidus pauculus. C. pauculus montre une résistance aux aminosides, une bonne activité de la ciprofloxacine et du cotrimoxazole ainsi que du céfotaxime, du céfépime et de l'imipénème. La résistance de C. pauculus à certaines -lactamines est liée à une nouvelle oxacillinase, différente d'OXA-22 et d'OXA-60 décrites chez R. pickettii. Enfin, le séquençage partiel du gène de l'ARN 16S nous a permis de détecter d'autres espèces de Ralstonia dans les expectorations des patients souffrant de mucoviscidose.

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