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Cytogénétique des hémopathies malignes by Amel Sebaa

Cytogénétique des hémopathies malignes

by Amel Sebaa
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Book cover type: Paperback
  • ISBN13: 9786208822590
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Editions Universitaires Europeennes
  • Publisher Imprint: Editions Universitaires Europeennes
  • Publication Date:
  • Pages: 124
  • Original Price: GBP 52.98
  • Language: French
  • Edition: N/A
  • Item Weight: 177 grams
  • BISAC Subject(s): Life Sciences / Biology

Dans les h�mopathies malignes, de nombreuses anomalies chromosomiques de nombre et surtout de structure, peuvent �tre identifi�es. Elles ont la particularit� d'�tre acquises et d'�voluer de fa�on clonale. Dans les tumeurs solides, diff�rents types d'anomalies chromosomiques ont �t� identifi�es. En plus des donn�es cytologiques et histologiques, l'identification d'une anomalie g�n�tique fait partie int�grante de la d�marche diagnostique des h�mopathies malignes et de certaines tumeurs solide. L'identification de ces anomalies intervient �galement dans la stratification pronostique, les choix th�rapeutiques et permet l'�valuation de la maladie r�siduelle apr�s traitement. Les anomalies chromosomiques d�cel�es dans les h�mopathies malignes sont acquises (retreintes au clone malin), clonales, primaires ou secondaires. Les anomalies cytog�n�tiques primaires sont g�n�ralement sp�cifiques d'une entit� pathologique, alors que les anomalies secondaires peuvent �tre moins sp�cifiques; ces derni�res refl�tent une �volution du clone malin et t�moignent se son instabilit� g�n�tique.

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