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Das Membransyndrom Der Früh- Und Neugeborenen: Anatomie, Klinik, Ätiologie, Pathogenese Und Therapie Des Syndroms Der Pulmonalen Hyalinen Membranen Un by U. Keuth

Das Membransyndrom Der Früh- Und Neugeborenen: Anatomie, Klinik, Ätiologie, Pathogenese Und Therapie Des Syndroms Der Pulmonalen Hyalinen Membranen Un

by U. Keuth
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Book cover type: Paperback
  • ISBN13: 9783642860706
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Publication Date:
  • Pages: 154
  • Original Price: EUR 37.37
  • Language: German
  • Edition: Softcover Repri
  • Item Weight: 232 grams
  • BISAC Subject(s): General

Die Sauglingssterblichkeit ist heute weitgehend eine Neugeborenensterb- lichkeit geworden. Diese Verschiebung ist einerseits Folge der ruhmreichen Bekampfung der Sterblichkeit jenseits der Neugeborenenperiode, anderer- seits aber Zeichen dafiir, daB unseren prophylaktischen und therapeutischen Bemiihungen innerhalb der Neugeborenenperiode bisher vergleichsweise nur geringere Erfolge beschieden waren. Bei dem groBten Teil der Neugebore- nentodesfalle handelt es sich urn Friihgeborene. In iiber 30010 aller Friih- geborenensektionen, seltener auch bei reifen Neugeborenen, findet sich das anatomische Syndrom der pulmonalen hyalinen Membranen, sei es als Haupt- oder als Nebenbefund. Es hangt, wie gezeigt werden wird, eng zusammen mit dem Problem der intrauterinen und postnatalen akuten und chronis chen asphyktischen Storungen. Schon von der Statistik her gesehen haben wir es also bei dem Membransyndrom und verwandten Syndromen, wie "respiratory distress syndrome", "congestive pulmonary failure", "chro- nischer Asphyxie" u. a., mit einem dringenden padiatrischen Problem zu tun. Die erste Beschreibung hyaliner Membranen in den Lungen von zwei Neugeborenen durch HOCHHEIM im Jahre 1903 hat wenig Beachtung ge- funden. Erst 1925 wieder befaBten sich JOHNSON U. MEYER damit und stellten erste Tierversuche zur Klarung der Ursache an. Sie wiesen auf die obligate Kombination mit Atelektasen hin, wahrend auf die typische Dreier- kombination des anatomischen Vollbildes mit vascularer Kongestion, Atel- ektasen und Membranen erst spater aufmerksam gemacht wurde. Abgesehen von wenigen Arbeiten, u. a. FARBER u. WILSON (1932) sowie ROSENTHAL (1935), begann die breitere Erkennung und Erforschung des anatomischen und klinischen Membransyndroms aber erst urn 1950.

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