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Depresja i samobójstwa by Emily Chen

Depresja i samobójstwa

by Emily Chen
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Book cover type: Paperback
  • ISBN13: 9786209520150
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Wydawnictwo Nasza Wiedza
  • Publisher Imprint: Wydawnictwo Nasza Wiedza
  • Publication Date:
  • Pages: 68
  • Original Price: GBP 38.19
  • Language: Polish
  • Edition: N/A
  • Item Weight: 105 grams
  • BISAC Subject(s): Life Sciences / Genetics & Genomics

Duże zaburzenia depresyjne (MDD) są jednym z najtrudniejszych do zbadania zaburzeń psychicznych. Jest to zaburzenie wielogenowe, kt�rego częstośc występowania w ciągu życia wynosi 10-15%, przy czym kobiety chorują dwukrotnie częściej niż mężczyźni, z nieznanych przyczyn. Wysoka częstośc występowania tego niezakaźnego, ale wyniszczającego zaburzenia w ciągu calego życia wymaga postęp�w w tej dziedzinie, aby można bylo opracowac lepsze leki terapeutyczne do skuteczniejszego leczenia pacjent�w. Badania asocjacyjne calego genomu dotyczące poważnej depresji nie przyniosly jeszcze znaczących wynik�w. Wynika to prawdopodobnie z niewielkiego wplywu poszczeg�lnych loci i/lub dużej heterogeniczności choroby. Dodatkowym czynnikiem komplikującym jest udzial czynnik�w niegenetycznych, takich jak zmienne środowiskowe. W rezultacie rozszyfrowanie architektury genetycznej jest trudne. Chociaż zar�wno geny, jak i środowisko są czynnikami wplywającymi na rozw�j MDD, niniejsza książka skupia się na genetyce tego zaburzenia. Istnieje pilna potrzeba zrozumienia genetycznych podstaw MDD, a naszym celem jest osiągnięcie tego poprzez wykorzystanie sekwencjonowania nowej generacji w celu odkrycia wariant�w genomowych i gen�w o zaburzonej regulacji, kt�re odgrywają rolę w rozwoju tej choroby.

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