Drying Technologies for Biotechnology and Pharmaceutical Applications
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A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals
Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues of why drying is required and what the critical considerations are for implementing this process operation during drug product development. Drying Technologies for Biotechnology and Pharmaceutical Applications discusses the state-of-the-art of established drying technologies like freeze- and spray- drying and highlights limitations that need to be overcome to achieve the future state of pharmaceutical manufacturing. The book also describes promising next generation drying technologies, which are currently used in fields outside of pharmaceuticals, and how they can be implemented and adapted for future use in the pharmaceutical industry. In addition, it deals with the generation of synergistic effects (e.g. by applying process analytical technology) and provides an outlook toward future developments. -Presents a full technical overview of well established standard drying methods alongside various other drying technologies, possible improvements, limitations, synergies, and future directionsSatoshi Ohtake, PhD, is the Senior Principal Scientist in Pharmaceutical Research & Development, BioTherapeutics Pharmaceutical Sciences at Pfizer in St. Louis (USA), and a member of the Scientific Advisory Committee for the Journal of Pharmaceutical Sciences.
Ken-ichi Izutsu, PhD, is a Section Chief Research Scientist at the National Institute of Health Sciences (Japan), and External Scientific Advisor of the Pharmaceuticals and Medical Devices Agency (Japan).
David Lechuga-Ballesteros, PhD, is a Principal Scientist at Pearl Therapeutics (USA), and serves as a member of the Editorial Advisory Board of the Journal of Pharmaceutical Sciences.
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