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Eisen Neurodegeneration by Khan, Mateen A.

Eisen Neurodegeneration

by Mateen A. Khan
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Book cover type: Paperback
  • ISBN13: 9786200476371
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Verlag Unser Wissen
  • Publisher Imprint: Verlag Unser Wissen
  • Publication Date:
  • Pages: 228
  • Original Price: GBP 77.0
  • Language: German
  • Edition: N/A
  • Item Weight: 341 grams
  • BISAC Subject(s): Life Sciences / Biology

Die Erforschung der Neurodegeneration durch Eisen hat in den letzten Jahrzehnten enorm zugenommen, und dieser Fortschritt wurde in zahlreichen Artikeln dokumentiert. Allerdings gibt es nur wenige Veröffentlichungen, die sich speziell mit der Eisenüberladung des Gehirns und der Überexpression des Alzheimer-Amyloid-Vorläuferproteins durch die Regulationswege des Iron Responsive Element (IRE) befassen, trotz der vielen Zusammenstellungen, die sich mit Themen des Eisenstoffwechsels und der Alzheimer-Krankheit befassen. Die Entschlüsselung der komplexen Mechanismen der Amyloid-Aggregation und der IRE-Signalwege ist für das Verständnis der Geheimnisse der Alzheimer-Progression von entscheidender Bedeutung.Dieses Buch, Iron Neurodegeneration, erklärt im Detail, wie der Eisenstoffwechsel reguliert wird und wie er die Entwicklung von neurodegenerativen Krankheiten beeinflusst. Vorrangiges Ziel ist es, zu erforschen, wie Amyloid-Aggregate über die IRE-mRNA-Translation entstehen, und potenzielle therapeutische Ziele für neurodegenerative Erkrankungen zu identifizieren. Dieses Buch richtet sich an eine breite Leserschaft: Fachleute werden die ausführlichen Beschreibungen und Diskussionen zu schätzen wissen, während Studenten, Forscher und Wissenschaftler, die neu auf dem Gebiet sind, von der umfassenden Einführung profitieren werden, die eine solide intellektuelle Grundlage bietet.

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