Évolution moléculaire du syndrome du calice gonflé ICS chez le Withania
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Le syndrome du calice gonflé (ICS), une nouveauté morphologique chez les Solanacées, est contrôlé par l'expression d'un gène à boîte MADS, MPF2-like (WSA206), dans les tissus floraux de Withania. En explorant la riche diversité de la morphologie du calice dans les taxons apparentés, il est démontré que la duplication du gène MPF2-like chez les Withaninae a fourni un terrain de jeu important pour de nouvelles innovations évolutives. La sous-(néo)-fonctionnalisation et la perte de gènes ont été très importantes, en conjonction avec la sélection darwinienne positive, dans l'évolution de l'ICS. La divergence d'expression dans les gènes de type MPF2 due à la perte réciproque d'éléments cis-régulateurs a ajouté aux variations génétiques et phénotypiques et a renforcé le potentiel de la sélection naturelle pour l'évolution adaptative de l'ICS. En outre, ces résultats donnent un aperçu de l'intégration des voies de développement floral et hormonal dans le développement de l'ICS et permettent de mieux comprendre l'importance de la polyploïdie chez les plantes. Les résultats rapportés ici expliqueront non seulement comment la nouveauté du calice a été façonnée et maintenue chez ces plantes, d'une manière très explicite, mais fourniront également un bel exemple d'utilisation de mutants évolutifs sauvages pour disséquer les variations de caractères complexes.
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