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G-Quadruplex DNA: Methods and Protocols by Peter Baumann

G-Quadruplex DNA: Methods and Protocols

by Peter Baumann
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Book cover type: Paperback
  • ISBN13: 9781493956395
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Springer
  • Publisher Imprint: Humana
  • Publication Date:
  • Pages: 276
  • Original Price: EUR 109.99
  • Language: English
  • Edition: Softcover Repri
  • Item Weight: 515 grams
  • BISAC Subject(s): Life Sciences / Genetics & Genomics, Life Sciences / Cell Biology, and Life Sciences / Molecular Biology

From the Back Cover

Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In G-Quadruplex DNA: Methods and Protocols, experts in the field present a collection of detailed techniques for studying G-quartet formation, dynamics, and molecular recognition. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, G-Quadruplex DNA: Methods and Protocols promises to be a useful resource for those familiar with G-quartets as well as an easy entry point for those researchers from diverse fields who are just developing an interest in the exciting implications of G-quadruplex DNA.

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