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Genome-Scale Algorithm Design by Veli Mäkinen

Genome-Scale Algorithm Design

by Veli Mäkinen , Djamal Belazzougui , Fabio Cunial
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Book cover type: Hardcover
  • ISBN13: 9781009341233
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Cambridge University Press
  • Publisher Imprint: Cambridge University Press
  • Publication Date: N/A
  • Pages: 470
  • Original Price: GBP 54.99
  • Language: English
  • Edition: 2nd Revised Edition
  • Item Weight: 944 grams
  • BISAC Subject(s): Life Sciences / Biochemistry

Presenting the fundamental algorithms and data structures that power bioinformatics workflows, this book covers a range of topics from the foundations of sequence analysis (alignments and hidden Markov models) to classical index structures (k-mer indexes, suffix arrays, and suffix trees), Burrows-Wheeler indexes, graph algorithms, network flows, and a number of advanced omics applications. The chapters feature numerous examples, algorithm visualizations, and exercises, providing graduate students, researchers, and practitioners with a powerful algorithmic toolkit for the applications of high-throughput sequencing. An accompanying website (www.genome-scale.info) offers supporting teaching material. The second edition strengthens the toolkit by covering minimizers and other advanced data structures and their use in emerging pangenomics approaches.

Belazzougui, Djamal: - Djamal Belazzougui is a permanent researcher at the Research Centre for Scientific and Technical Information in Algiers, Algeria. He worked in the Genome-Scale Algorithmics group at the University of Helsinki as a postdoctoral researcher from 2012 to 2015. His research topics include hashing, succinct and compressed data structures, string algorithms, and bioinformatics.

Cunial, Fabio: - Fabio Cunial is a computational scientist at the Broad Institute of MIT and Harvard. He has served as a postdoctoral researcher at the Genome-Scale Algorithmics group at the University of Helsinki as well as at the Myers lab in Dresden.

Mäkinen, Veli: - Veli Mäkinen is Professor of Computer Science at the University of Helsinki, where he leads a research team on genome-scale algorithmics. He has taught advanced courses on algorithm design and analysis, string processing, data compression, and algorithmic genome analysis, as well as introductory courses on bioinformatics.

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