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Génomique Du Virus de l'Hépatite E by Bouquet-J

Génomique Du Virus de l'Hépatite E

by Bouquet-J
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Book cover type: Paperback
  • ISBN13: 9783838178639
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Omniscriptum
  • Publisher Imprint: Omniscriptum
  • Publication Date:
  • Pages: 188
  • Original Price: GBP 49.0
  • Language: French
  • Edition: N/A
  • Item Weight: 282 grams
  • BISAC Subject(s): Life Sciences / Microbiology

En France, le virus de l'hépatite E (VHE) est responsable de cas d'hépatites aigües sporadiques dont les origines et les modes de transmission sont incertains. Or, le VHE est le seul virus des hépatites à infecter d'autres espèces animales que l'homme. Les objectifs de cette thèse ont été d'évaluer le risque de transmission zoonotique du VHE porcin pour l'Homme en France par des méthodes de génomique. Ces travaux développés en 4 parties ont permis de montrer le risque zoonotique du VHE du porc consommé en France et son adaptation génomique complète à ses deux espèces hôtes. Le VHE est un virus zoonotique à ARN particulier dont la variabilité génétique dépend de son épidémiologie singulière, qui inclue la possibilité de transmissions alimentaires à partir d'un réservoir animal domestique. Ce travail permet enfin de poser les perspectives d'études phénotypiques du VHE.

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