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Geriatrische Beurteilung des multiplen Myeloms by Latifa Khelifa, Hela Ghedira

Geriatrische Beurteilung des multiplen Myeloms

by Latifa Khelifa , Hela Ghedira
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Book cover type: Paperback
  • ISBN13: 9786209379437
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Verlag Unser Wissen
  • Publisher Imprint: Verlag Unser Wissen
  • Publication Date:
  • Pages: 52
  • Original Price: GBP 38.19
  • Language: German
  • Edition: N/A
  • Item Weight: 82 grams
  • BISAC Subject(s): General

Das multiple Myelom ist eine H�mopathie bei �lteren Menschen. Die Untersuchung der Gebrechlichkeit ist bei der Behandlung dieser Patienten von gro em Interesse. Ziel unserer Studie ist es, die epidemiologischen, diagnostischen und prognostischen Merkmale �lterer Patienten mit multiplem Myelom zu bestimmen und die Auswirkungen von Gebrechlichkeitstests auf das Gesamt�berleben, die behandlungsbedingte Toxizit�t und den ereignisfreien Verlauf zu bewerten.Das mediane Alter betrug 73 Jahre (Extreme: 65-89 Jahre). Der h�ufigste Entdeckungsgrund waren Knochenschmerzen in 40% der F�lle. Eine Nierenbeteiligung wurde bei 42% der Patienten festgestellt. Die H�lfte der Patienten wurde nach dem MPT-Protokoll (Melphalan-Prednison-Thalidomid) behandelt. Die am h�ufigsten berichtete Toxizit�t war neurologischer Art. Die schwersten Toxizit�ten waren infekti�ser Art. Eine Untersuchung der Gebrechlichkeit w�re von gro em Interesse f�r die Ausrichtung der therapeutischen Betreuung in dieser Altersgruppe. Ein Anfangsscore, der die Gebrechlichkeitstests und die prognostischen Faktoren der H�mopathie ber�cksichtigt, h�tte einen besseren Vorhersagewert in Bezug auf das Gesamt�berleben und das ereignisfreie �berleben.

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