Indikation Und PRAXIS Cerebroprotektiver Maßnahmen in Der Neurochirurgie: Bericht Über Eine Gesprächsrunde Am 8. Juni 1985 in Frankfurt
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Die Pravention und Behandlung bleibender neurologischer Ausfallserscheinungen infolge eines akuten perioperativen Sauerstoffmangels zentralnervoser Strukturen ist in den letzten Jahren eine der Hauptaufgaben anasthesiologischen Managements geworden, insbesondere angesichts der erfolgreichen Weiterentwicklung cardio- pulmonaler Reanimationstechniken. Neurochirurgische Eingriffe sind naturgemaB in besonderer Weise mit der Problematik cerebraler ischamischer oder hypoxischer Hypoxie verkniipft, z. B. durch intraoperatives Gewebstrauma, durch GefiiBligatu- ren, durch Himschwellung, durch Luftembolie bei Operationen in sitzender Posi- tion oder auch begleitend zu tiefer kontrollierter Hypotension. Unter diesem Aspekt bieten sie fiir den betreuenden Anasthesisten eine besondere Herausforde- rung, der er sowohl durch allgemeine MaBnahmen im Sinne der Erhaltung ausrei- chender lokaler und globaler cerebraler Sauerstoffverfiigbarkeit als auch durch spezifisch, e MaBnahmen fUr eine mogliche Verbesserung der cerebralen Ischamieto- leranz zu begegnen sucht. Urn neueste Entwicklungen auf dem Gebiet des perioperativen Himschutzes zu diskutieren, trafen sich in Frankfurt zu einer Gesprachsrunde Neurochirurgen und Anasthesisten zum Erfahrungsaustausch auf diesem fiir beide Disziplinen wichtigen Gebiet. Basierend auf den Ergebnissen eigener klinischer Untersuchungen sowie auf neueren Aspekten zur Pathophysiologie, Pathobiochemie und Pharmakothera- pie des cerebralen Oz-Mangelsyndroms sollte versucht werden, 'Ansatzpunkte fUr neue therapeutische Richtlinien auszuarbeiten, die sich zukiinftig vielleicht zu einem erfolgversprechenden Konzept der Pravention und Behandlung cerebral-ischami- scher Verletzungen ausbauen lassen. Die von den Referenten gehaltenen Vortrage sowie wesentliche Punkte der nachfolgenden Diskussion sind Inhalt dieses Buches. Die Herausgeber danken an dieser Stelle der Eli Lilly GmbH, Bad Homburg, fiir die groBziigige Unterstiitzung der Veranstaltung. Die Herausgeber Inhaltsverzeichnis Physiologische Grundlagen von hirnprotektiven MaBnahmen D. HEUSER, B. KOTILER ..............-.....
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