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Indução de doenças hepáticas experimentais by Jihan Hussein

Indução de doenças hepáticas experimentais

by Jihan Hussein , Mona Anwar El-Banna , Safaa Metwally Morsy
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Book cover type: Paperback
  • ISBN13: 9786208968717
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edicoes Nosso Conhecimento
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Publication Date:
  • Pages: 84
  • Original Price: GBP 31.23
  • Language: Portuguese
  • Edition: N/A
  • Item Weight: 123 grams
  • BISAC Subject(s): Life Sciences / Biochemistry

As doen�as hep�ticas levam a v�rias altera��es patol�gicas, como f�gado gorduroso, aumento de ROS ou stress oxidativo, necrose das c�lulas hep�ticas, hepatite, esteatose, colestase, les�es vasculares e granuloma e doen�as veno-oclusivas, aumento do n�vel de marcadores inflamat�rios, carcinoma hepatocelular, que produzem hipertens�o portal e insufici�ncia hep�tica. Modelos animais s�o uma ferramenta importante para identificar a causa da les�o hep�tica e a patog�nese. Neste projeto, destacamos algumas doen�as hep�ticas experimentais induzidas por produtos qu�micos. A partir desses produtos qu�micos: metais pesados, tetracloreto de carbono, �lcool, paracetamol, cloridrato de D-galactosamina (DGa1N) e lipopolissacar�deo (LPS). O DGa1N e o LPS juntos nos fornecem um modelo experimental de hepatite hep�tica muito semelhante � hepatite viral em humanos, tanto do ponto de vista morfol�gico quanto funcional.

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