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Interactions contenant-contenu by Souissi, Nour Elhouda

Interactions contenant-contenu

by Nour Elhouda Souissi , Mohamed Hedi Ben Cheikh
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Book cover type: Paperback
  • ISBN13: 9783639524482
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Editions Universitaires Europeennes
  • Publisher Imprint: Editions Universitaires Europeennes
  • Publication Date:
  • Pages: 92
  • Original Price: GBP 50.0
  • Language: French
  • Edition: N/A
  • Item Weight: 146 grams
  • BISAC Subject(s): Pharmacology

Dans le secteur pharmaceutique, les interactions contenant-contenu désignent le transfert de substances entre un équipement de fabrication, un conditionnement ou un dispositif médical, et le médicament. Ces phénomènes incluent l'adsorption des principes actifs ou des excipients sur les parois du contenant, leur pénétration à l'intérieur des matériaux ou leur diffusion dans l'environnement extérieur. De surcroit, ces phénomènes incluent la migration de substances du contenant vers le médicament ou du milieu extérieur vers ce dernier. De telles interactions peuvent compromettre la qualité, l'efficacité et l'innocuité des produits pharmaceutiques, provoquant des effets indésirables potentiellement graves pour les patients, tels que des modifications de l'efficacité thérapeutique ou des réactions toxiques. Dans ce travail, nous avons rapporté des exemples d'interaction contenant-contenu en précisant les circansatances de leurs survenues, les méthodologies de leurs études et leurs impacts tant sur le médicament que sur le patient.

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