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IR Genes: Past, Present, and Future by Carl W. Pierce

IR Genes: Past, Present, and Future

by Carl W. Pierce
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Book cover type: Hardcover
  • ISBN13: 9780896030503
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Springer
  • Publisher Imprint: Humana
  • Publication Date:
  • Pages: 622
  • Original Price: EUR 149.99
  • Language: English
  • Edition: 1983
  • Item Weight: 1080 grams
  • BISAC Subject(s): Animals / Mammals and Immunology

The Fifth Ir Gene Workshop was held at the Chase-Park Plaza Hotel, St. Louis, MO, August 28-31, 1982; 240 scientists participated in the Workshop. The man- uscripts compiled in this book describe the state of the art concerning Ir genes. Although the notion of Ir Genes: Past, Present, and Future has not been ad- dressed specifically by each author, the reader is certain to get this flavor from the contributions. In this Preface, we have tried to summarize some of the salient ob- servations and discussions from the Workshop. The mUltiple genes of the I region have been defined traditionally by serolog- ical analysis of intra-H-2 recombinant mice and the pattern of immune responses to certain antigens developed by these recombinant mice. The application of sev- eral new techniques, such as gene cloning and DNA sequencing, production of T and B cell hybridomas, and development of cloned T cell lines has changed this tradition and introduced a new phase into the analysis of the I region, Ia antigens, and Ir genes.

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