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KRAS: Methods and Protocols

by Andrew G. Stephen , Dominic Esposito
Save 35% Save 35%
Current price ₹11,643.00
Original price ₹17,911.00
Original price ₹17,911.00
Original price ₹17,911.00
(-35%)
₹11,643.00
Current price ₹11,643.00

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Book cover type: Paperback
  • ISBN13: 9781071638248
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Humana
  • Publisher Imprint: Humana
  • Publication Date:
  • Pages: 376
  • Original Price: EUR 159.99
  • Language: English
  • Edition: N/A
  • Item Weight: 668 grams
  • BISAC Subject(s): Oncology / General

This volume details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, KRAS: Methods and Protocols aims to provide methods that will be instrumental in the development of future clinically approved KRAS therapeutics.

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