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L-Asparaginase: Ein Mittel gegen Leukämie by Kuldeep Luhana, Akash Dave, Kruti Patel

L-Asparaginase: Ein Mittel gegen Leukämie

by Kuldeep Luhana , Akash Dave , Kruti Patel
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Book cover type: Paperback
  • ISBN13: 9786209331497
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Verlag Unser Wissen
  • Publisher Imprint: Verlag Unser Wissen
  • Publication Date:
  • Pages: 52
  • Original Price: GBP 31.23
  • Language: German
  • Edition: N/A
  • Item Weight: 82 grams
  • BISAC Subject(s): General

Krebs ist eine der t�dlichen Krankheiten, die weltweit auftritt und bei der K�rperzellen abnormal werden, sich kontinuierlich teilen und Tumore bilden. F�r Krebs werden verschiedene Behandlungsmethoden angewendet, wie Chemotherapie, Strahlentherapie und Chirurgie. Alle diese Methoden haben gewisse Vorteile, Einschr�nkungen und Nebenwirkungen. Daher besteht Bedarf an wirksamen, aber sicheren Therapeutika zur Behandlung von Krebserkrankungen. L-Asparaginase hat sich als neuartiges Therapeutikum gegen Blutkrebs, d. h. Leuk�mie, erwiesen. Es katalysiert die Deamidierung von L-Asparagin zu L-Aspartat und Ammoniak (L-Asparagin-Amidohydrolase; E.C. 3.5.1.1). Mehrere Arten von Mikroorganismen, darunter Pilze, Bakterien, Hefen und verschiedene Pflanzen, produzieren dieses Enzym, w�hrend es im menschlichen K�rper vollst�ndig fehlt. Da dieses Enzym im Vergleich zu anderen Chemotherapeutika starke krebsbek�mpfende Eigenschaften aufweist und keine Nebenwirkungen hat (in einigen Studien wurde gelegentlich �ber leichte allergische Reaktionen berichtet), hat es Wissenschaftler aus dem Bereich der Biologie dazu veranlasst, nach m�glichen Quellen f�r dieses Enzym zu suchen.

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