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L-asparaginase: un agent anti-leucémique by Kuldeep Luhana, Akash Dave, Kruti Patel

L-asparaginase: un agent anti-leucémique

by Kuldeep Luhana , Akash Dave , Kruti Patel
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Book cover type: Paperback
  • ISBN13: 9786209341731
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Editions Notre Savoir
  • Publisher Imprint: Editions Notre Savoir
  • Publication Date:
  • Pages: 52
  • Original Price: GBP 31.23
  • Language: French
  • Edition: N/A
  • Item Weight: 82 grams
  • BISAC Subject(s): General

Le cancer est l'une des maladies mortelles pr�sentes dans le monde entier, dans laquelle les cellules du corps deviennent anormales, se divisent continuellement et forment des tumeurs. Divers traitements sont utilis�s pour lutter contre le cancer, tels que la chimioth�rapie, la radioth�rapie et la chirurgie. Toutes ces m�thodes pr�sentent des avantages, des limites et des effets secondaires. Il est donc n�cessaire de trouver un agent th�rapeutique puissant mais s�r pour traiter les cancers. La L-asparaginase s'est av�r�e �tre un nouvel agent th�rapeutique contre le cancer du sang, c'est-�-dire la leuc�mie. Elle catalyse la d�samidation de la L-asparagine en L-aspartate et en ammoniac (L-asparagine amidohydrolase; E.C. 3.5.1.1). Plusieurs types de micro-organismes, notamment des champignons, des bact�ries, des levures et diverses plantes, produisent cette enzyme, alors qu'elle est totalement absente chez l'�tre humain. Comme cette enzyme poss�de de puissantes propri�t�s anticanc�reuses et ne pr�sente aucun effet secondaire (� l'exception de r�actions allergiques mineures signal�es dans certaines �tudes) par rapport � d'autres agents chimioth�rapeutiques, elle a attir� l'attention des scientifiques du domaine biologique qui cherchent � d�couvrir des sources potentielles de cette enzyme.

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