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L'accuratezza del test Gene Xpert di Cepheid by Lusiba, John

L'accuratezza del test Gene Xpert di Cepheid

by John Lusiba
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Book cover type: Paperback
  • ISBN13: 9786202209953
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 47.76
  • Language: Italian
  • Edition: N/A
  • Item Weight: 109 grams
  • BISAC Subject(s): Life Sciences / Biology

Il versamento pleurico tubercolare � una causa comune di ricovero dei pazienti nell'ospedale Mulago, specialmente tra i pazienti affetti da HIV. L'istologia e la coltura del tessuto pleurico per MTB, il gold standard, comportano una procedura invasiva che richiede competenze specifiche e richiede molto tempo. Abbiamo testato l'accuratezza diagnostica del Gene Xpert specifico per MTB di Cepheid, un test in tempo reale basato sulla PCR che utilizza il liquido pleurico, con l'obiettivo di ottenere un metodo pi� rapido, pi� facile da usare, accurato e meno invasivo nella diagnosi della tubercolosi pleurica nel nostro contesto. Questo test ha dimostrato di migliorare la diagnosi della tubercolosi polmonare con accuratezza e in meno di 2 ore. Piccoli studi pilota hanno riportato livelli variabili di accuratezza di questo test nella diagnosi della tubercolosi pleurica. Tuttavia, uno studio sudafricano condotto da Sven et al. nel 2011 ha dimostrato una sensibilit� del 25% e una specificit� del 100% su 20 campioni di pazienti con TB pleurica confermata. Obiettivi: Determinare l'accuratezza del test Gene Xpert specifico per la TB nella diagnosi della TB pleurica tra i pazienti adulti con sospetto versamento pleurico tubercolare che hanno frequentato il Servizio di Pneumologia dell'Ospedale Mulago durante il periodo di studio.

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