Ligand-Binding Basics: Evaluating Intermolecular Affinity, Specificity, Stoichiometry, and Cooperativity

Name: Ligand-Binding Basics: Evaluating Intermolecular Affinity, Specificity, Stoichiometry, and Cooperativity
Brand: Wiley
SKU: 9781119878421
Price: 6189.0 INR
Availability: InStock

by Jannette Carey

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ISBN13: 9781119878421
Binding: Hardcover
Subject: N/A
Publisher: Wiley
Publisher Imprint: Wiley
Publication Date: May 1, 2025
Pages: 256
Original Price: USD 97.95
Language: English
Edition: N/A
Item Weight: 788 grams
BISAC Subject(s): Chemistry / Physical & Theoretical

About The Book

A concise and accessible textbook covering ligand-binding theory in chemistry, biology, and drug development

In Ligand-binding Basics: Evaluating Intermolecular Affinity, Specificity, Stoichiometry, and Cooperativity, accomplished chemist Jannette Carey introduces ligand binding in a thorough and practical way for those new to the topic, as well as anyone seeking a connection between theory and experiment. Using a minimum of mathematical formalism, this book offers analytical rigor while remaining accessible to non-specialist practitioners. It provides readers with the skills they need to analyze their own binding data or published results, helping them develop an intuitive grasp of ligand-binding phenomena integrated with structural and thermodynamic understanding.

Topics covered include: *Application of the principles of equilibrium, mass action, and mass balance to derive the basic equations that describe all binding processes *Recommended approaches for plotting and graphical analysis of binding data *Strategies for designing, analyzing, interpreting, and troubleshooting experiments from the perspective of ligand-binding theory *Review of selected examples that illustrate integration of structural and thermodynamic analysis

Perfect for students and educators in chemistry, biochemistry, molecular biology, and pharmaceutical science, Ligand-binding Basics will also appeal to practitioners who aim to study ligand binding in any molecular system.

About The Author

Jannette Carey has been a member of the Chemistry faculty at Princeton University for over thirty years, where she developed and teaches a two-term sequence in biophysical chemistry that is accessible to early graduate and advanced undergraduate students in a wide range of disciplines. Her biophysical research is focused on unifying the thermodynamic and structural basis for macromolecular interactions

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