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Matrix Metalloproteinases and Timps by J. F. Woessner, Fred Woessner, Hideaki Nagase

Matrix Metalloproteinases and Timps

by J. F. Woessner , Fred Woessner , Hideaki Nagase
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Book cover type: Paperback
  • ISBN13: 9780198502685
  • Binding: Paperback
  • Subject: N/A
  • Publisher: OUP Oxford
  • Publisher Imprint: OUP Oxford
  • Publication Date:
  • Pages: 238
  • Original Price: USD 71.0
  • Language: English
  • Edition: Revised
  • Item Weight: 431 grams
  • BISAC Subject(s): Life Sciences / Biochemistry

The matrix metalloproteinases (MMPs) are a large family of enzymes that breakdown different components of the extracellular matrix. Their catalytic activity is dependent a metal ion, usually zinc. This issue of the Protein Profiles covers the sequence information, three-dimensional structures, activation, protein substrates, specificity requirements, inhibition, and biological roles of all the currently identified MMPs. The action of these enzymes must be carefully regulated. One way the cell does this, is by releasing inhibitory molecules known as tissue inhibitors of metalloproteinases (TIMPs). This volume contains information on the sequences, three-dimensional structures, and biological roles of the 4 known classes of TIMP. Matrix metalloproteinases will therefore be an invaluable source of data for all researchers interested in MMPs and TIMPs.

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