Menopausa: Etiologia, Sintomas e Terapia Hormonal na Prática Clínica
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A menopausa � uma transi��o natural, relacionada com a idade, marcada pelo decl�nio da fun��o ov�rica e pela cessa��o permanente da menstrua��o, normalmente entre os 45 e os 55 anos. Isto leva � redu��o do estrog�nio e da progesterona, afectando v�rios sistemas do corpo. A priva��o hormonal provoca sintomas como afrontamentos, suores noturnos, s�ndrome geniturin�rio da menopausa (SGM), altera��es de humor, problemas de sono, decl�nio cognitivo e desconforto m�sculo-esquel�tico. A perda de estrog�nio tamb�m aumenta o risco de doen�as cardiovasculares (DCV), osteoporose, diabetes e doen�as neurodegenerativas. A terapia hormonal (TH) � o padr�o de ouro para sintomas moderados a graves, especialmente vasomotores e urogenitais. Quando iniciada em mulheres saud�veis com menos de 60 anos ou no prazo de 10 anos ap�s o in�cio da menopausa, a TH pode oferecer benef�cios adicionais, tais como uma melhor sa�de �ssea, apoio cognitivo e prote��o contra as doen�as cardiovasculares. � crucial uma abordagem personalizada e baseada no risco, adaptando o tipo, a dose e a administra��o da TH �s necessidades individuais. Embora n�o seja apenas para a preven��o de doen�as, a utiliza��o adequada da TH melhora a qualidade de vida e promove um envelhecimento saud�vel.
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