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Metformina jako lek wewnątrzkanalowy by Rishu Singh

Metformina jako lek wewnątrzkanalowy

by Rishu Singh
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Book cover type: Paperback
  • ISBN13: 9786209492532
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Wydawnictwo Nasza Wiedza
  • Publisher Imprint: Wydawnictwo Nasza Wiedza
  • Publication Date:
  • Pages: 148
  • Original Price: GBP 59.94
  • Language: Polish
  • Edition: N/A
  • Item Weight: 209 grams
  • BISAC Subject(s): Dentistry / General

Metformina jako lek wewnątrzkanalowy: A Paradigm Shift in Treating Apical Periodontitis przedstawia doglębną i opartą na dowodach analizę metforminy jako nowego i biologicznie aktywnego leku wewnątrzkanalowego w nowoczesnej terapii endodontycznej. Choc tradycyjnie przepisywana jako doustny lek przeciwcukrzycowy pierwszego rzutu, metformina stala się lekiem o wieloaspektowych wlaściwościach biologicznych, kt�re wykraczają daleko poza kontrolę glikemii. Ostatnie badania wykazaly jej dzialanie przeciwbakteryjne, przeciwzapalne, immunomodulujące i osteogenne, co czyni ją obiecującym kandydatem do miejscowego stosowania w leczeniu zapalenia przyzębia wierzcholkowego. Książka kompleksowo bada profil farmakologiczny metforminy, podkreślając jej mechanizmy dzialania istotne dla patologii endodontycznej. Szczeg�lowo om�wiono zdolnośc metforminy do modulowania szlak�w zapalnych, tlumienia cytokin prozapalnych i aktywacji kinazy bialkowej aktywowanej monofosforanem adenozyny (AMPK), podkreślając jej rolę w kontrolowaniu zapalenia okolowierzcholkowego. Dodatkowo, tekst analizuje aktywnośc przeciwdrobnoustrojową metforminy przeciwko patogenom endodontycznym i jej potencjal do zakl�cania tworzenia biofilmu w systemie kanal�w korzeniowych.

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