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Methodologies for Metabolomics: Experimental Strategies and Techniques by Norbert Lutz, Jonathan Sweedler, Ron Wevers

Methodologies for Metabolomics: Experimental Strategies and Techniques

by Norbert Lutz , Jonathan Sweedler , Ron Wevers
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Book cover type: Hardcover
  • ISBN13: 9780521765909
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Cambridge University Press
  • Publisher Imprint: Cambridge University Press
  • Publication Date:
  • Pages: 640
  • Original Price: GBP 169.0
  • Language: English
  • Edition: 1
  • Item Weight: 1452 grams
  • BISAC Subject(s): Biotechnology

Metabolomics, the global characterization of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways, and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites including nuclear magnetic resonance and mass spectrometry are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples, and diseases, ranging from in vivo metabolomics in humans and animals, to in vitro analysis of tissue samples, cultured cells and biofluids.

Sweedler, Jonathan V.: - Jonathan V. Sweedler is the James R. Eiszner Family Professor of Chemistry and the Director of the School of Chemical Sciences at the University of Illinois at Urbana-Champaign, USA. His major research efforts involve developing new approaches for small-volume peptidomics and metabolomics and the application of these technologies to study novel neuro-chemical pathways. Professor Sweedler has published more than 350 manuscripts, book chapters and reviews and has presented 350 invited lectures relate to research in these areas. He is Editor-in-Chief of Analytical Chemistry.

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