Metipranolol: Pharmakologie Der Betablocker Und Ophthalmologische Anwendung Von Metipranolol
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Von der Entdeckung einer Substanz und deren verschiedenen Wir- kungen, bzw. einer ganz bestimmten von diesen, bis zum Medi- kament der taglichen Praxis ist ein weiter Weg. Er fiihrt vom Chemi- ker iiber den Pharmakologen und den Pharmazeuten, urn nur die wichtigsten Stationen zu nennen, zum Arzt. Vor der allgemeinen Einfiihrung eines Praparats steht die klinische Priifung, urn die am Tier gewonnenen Erkenntnisse und die an die Entwicklung gekniipf- ten Erwartungen zu kontrollieren sowie diese womoglich urn neue Einsichten zu bereichern, bis schliemich Wirkungen und Nebenwir- kungen, Indikationen und Kontraindikationen sowie eine im gege- benen Rahmen liegende Unbedenklichkeit fiir die vorgesehene An- wen dung und deren Art und Weise, einschlielSlich Zubereitungsfor- men und Dosierungen, in ausreichendem MalSe bekannt sind. Dann erst kann die Zulassung und Einfiihrung als Handelspraparat er- folgen. Auch die unlangst in den Verkehr gebrachten Metipranolol-Augen- tropfen haben dies en Weg durchschritten. Eine ganze Reihe von For- schern an verschiedensten Platzen haben an diesem ProzelS mitge- wirkt, die sich im Januar 1983 in Berlin auf Einladung der Her- stellerfirma, Dr. Gerhard Mann, zu einem Symposium zusammen- gefunden haben, urn iiber die Substanz und die mit ihr erworbenen Erfahrungen zu berichten und zu diskutieren. Die Beitrage erscheinen so intert: ssant und auch praktisch wichtig, dalS ihre Publikation in gedruckter Form erfolgen solI, urn sie allgemein zuganglich zu machen. Das so entstandene' B1: lch wird hiermit vorgelegt.
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