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Misoprostol Dans La Maturation Cervicale by Bergaoui, Hayfa

Misoprostol Dans La Maturation Cervicale

by Hayfa Bergaoui , Imen Ghadhab , Yessine Belhaj
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Book cover type: Paperback
  • ISBN13: 9786206723738
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Editions Universitaires Europeennes
  • Publisher Imprint: Editions Universitaires Europeennes
  • Publication Date:
  • Pages: 72
  • Original Price: GBP 37.0
  • Language: French
  • Edition: N/A
  • Item Weight: 118 grams
  • BISAC Subject(s): General

La rupture prématurée des membranes est une situation obstétricale fréquente. Elle touche 8 à 10% des grossesses à terme.Sa PEC optimale est controversé. Parmi les moyens utilisés dans la maturation cervicale: les prostaglandines, dont la Dinoprostone qui en est la molécule de référence.Matériel et méthodes Il s'agit d'un essai clinique prospectif, randomisé réalisé au centre de maternité et de néonatologie du CHU de Monastir sur une période de 1 année (janvier-décembre 2017). Incluant 240 parturientes présentant une RPM à terme et reparties en 2 groupes: Le groupe voie orale: ayant reçu 20mcg/ 2h de misoprostol en solution par voie orale (maximum 6 doses) et le groupe voie vaginale: ayant reçu 50mcg/ 6h de misoprostol par voie vaginale (maximum 4 doses).Conclusion Au terme de ce travail, l'utilisation du Misoprostol en faibles doses par VO pour la maturation cervicale à terme, avec PDER, est aussi efficace que la VV en terme de taux d'accouchements dans 24 h, alors qu'elle est en légère avance à 12 h (44% versus 33%) sans que la différence ne soit significative.

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