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Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants by Yvonne Will

Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants

by Yvonne Will
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Book cover type: Hardcover
  • ISBN13: 9781119329701
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Wiley
  • Publisher Imprint: Wiley
  • Publication Date:
  • Pages: 816
  • Original Price: USD 416.95
  • Language: English
  • Edition: N/A
  • Item Weight: 490 grams
  • BISAC Subject(s): Chemistry / Toxicology, Life Sciences / Molecular Biology, and Life Sciences / Biochemistry

Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.

•    Covers both basic science and applied technology / methods
•    Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects
•    Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development
•    Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria

Yvonne Will, PhD, is a Senior Director and the Head of Science and Technology Strategy, Drug Safety Research and Development at Pfizer, Connecticut, USA. In addition to the prior edition of this book, she co-edited Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers(Wiley, 2016).

James A. Dykens, PhD, oversees EyeCyte Therapeutics, a start-up developing treatments for progressive blinding diseases via targeting mitochondrial dysfunction. He co-edited the first edition of this book.

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