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Modélisation moléculaire et développement du médicament by Bougniot-O

Modélisation moléculaire et développement du médicament

by Bougniot-O
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Book cover type: Paperback
  • ISBN13: 9786131512353
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Omniscriptum
  • Publisher Imprint: Omniscriptum
  • Publication Date:
  • Pages: 76
  • Original Price: GBP 23.0
  • Language: French
  • Edition: N/A
  • Item Weight: 123 grams
  • BISAC Subject(s): Pharmacology

La synthèse du médicament est un processus pouvant durer plus de 10 ans et demandant des centaines de millions de Dollars d'investissement. Le choix d'un bon candidat, c'est à dire d'une molécule médicamenteuse efficace et rentable, est un enjeu majeur de la recherche pharmaceutique. En cas d'erreur, ce sont des années et des investissements colossaux qui seront perdus pour rien ou presque. Les techniques de modélisation moléculaire apparues il y a quelques années à peine, permettent de créer des modèles, des millions de modèles, dans lesquels plusieurs critères physico-chimiques seront étudiés et mesurés afin d'augmenter les chances de succès dans le choix de la molécule candidate. Cette étude primordiale précèdera les longues étapes de synthèse chimique, puis d'essais cliniques, amenant parfois à la mise sur le marché d'une nouvelle spécialité pharmaceutique. Ces technologies ultra modernes et en perpétuelle évolution sont désormais utilisées par tous les plus grands laboratoires pharmaceutiques mondiaux, mais les prédictions In Silico sont elles infaillibles?

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