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Moderne Migränebehandlung: Molekulare Mechanismen, Neuromodulation und Präzisionsmedizin by Lillian Midtgaard

Moderne Migränebehandlung: Molekulare Mechanismen, Neuromodulation und Präzisionsmedizin

by Lillian Midtgaard
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Book cover type: Paperback
  • ISBN13: 9783691737424
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Bremen University Press
  • Publisher Imprint: Bremen University Press
  • Publication Date:
  • Pages: 110
  • Original Price: GBP 19.9
  • Language: German
  • Edition: N/A
  • Item Weight: 137 grams
  • BISAC Subject(s): General

Migr�ne l�sst sich heute besser kontrollieren als je zuvor. Doch ihr eigentliches Geheimnis liegt nicht in der Unterdr�ckung einzelner Symptome, sondern im Verst�ndnis ihrer systemischen Dynamik. Migr�ne ist weit mehr als Kopfschmerz. Sie ist eine komplexe neurologische Systemerkrankung, die neuronale Netzwerke, vaskul�re Mechanismen, Immunprozesse und genetische Pr�dispositionen miteinander verbindet. Trotz jahrzehntelanger Forschung wurde sie lange missverstanden - als isoliertes Schmerzph�nomen, als psychosomatische Reaktion oder als blo e Gef� erkrankung. Dieses Buch zeichnet die wissenschaftliche Transformation des Migr�neverst�ndnisses nach - von den fr�hen vaskul�ren Hypothesen �ber die Entdeckung des CGRP-Systems bis hin zu modernen Netzwerkmodellen des Gehirns. Es analysiert die Rolle der Cortical Spreading Depression, die Dynamik der Chronifizierung, Mechanismen zentraler Sensitivierung und die komplexe Interaktion zwischen Hirnstamm, Thalamus und Kortex. Ein besonderer Schwerpunkt liegt auf den therapeutischen Innovationen der letzten Jahre: CGRP-Antik�rper, Gepants, Ditans, neuromodulatorische Verfahren sowie personalisierte Pr�ventionsstrategien. Das Werk beleuchtet nicht nur Wirkmechanismen, sondern auch klinische Studien, regulatorische Entwicklungen und die Perspektiven einer zuk�nftigen Pr�zisionsmedizin. Dieses Buch zeigt, wie aus einer episodischen St�rung ein chronisches Netzwerkph�nomen werden kann - und wie moderne Medizin beginnt, diesen Prozess gezielt zu modulieren. Bremen University Press hat seit 2005 �ber 5.500 Fachb�cher in verschiedenen Sprachen publiziert. Februar 2026

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