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Multiple Sequenzalignments: Welches Programm Passt Zu Meinen Daten? by Theodor Sperlea

Multiple Sequenzalignments: Welches Programm Passt Zu Meinen Daten?

by Theodor Sperlea
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Book cover type: Paperback
  • ISBN13: 9783662588109
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Springer Spektrum
  • Publisher Imprint: Springer Spektrum
  • Publication Date:
  • Pages: 102
  • Original Price: USD 19.99
  • Language: German
  • Edition: 1. Aufl. 2019
  • Item Weight: 177 grams
  • BISAC Subject(s): Life Sciences / Anatomy & Physiology

Dieses Buch ist ein praktischer Ratgeber f�r Biologinnen und Biologen, die Multiple Sequenzalignments (MSAs) f�r ihre Datenanalysen verwenden und einen verst�ndlichen �berblick �ber die vielen verschiedenen Programme suchen. Trotz ihres wichtigen Stellenwertes in der Datenanalyse herrscht Unsicherheit unter den Forschenden wie MSA-Programme genau funktionieren - ganz zu schweigen davon, wie und warum die unterschiedlichen Analysen zu verschiedenen Ergebnissen f�hren. Welches Programm ist f�r die Auswertung meiner Daten das richtige und wie kann ich sicherstellen, alle relevanten Erkenntnisse aus den Alignments gezogen zu haben? Dieses Buch bietet hilfreiche Erkl�rungen und Hintergr�nde ohne gro e bioinformatische Vorkenntnisse vorauszusetzen und f�hrt die Leserinnen und Leser langsam in die Thematik ein.Im ersten Teil des Buches werden die m�glichen Einsatzfelder wie auch die Formate, die �blicherweise von MSA-Programmen produziert werden, im Detail beschrieben. Ebensowerden auf unkomplizierte Weise die zentralen Algorithmen sowie die inneren Abl�ufe der g�ngigsten MSA-Programme der Vergangenheit und der Gegenwart in gr� erer Detailtiefe erkl�rt. Den zweiten Teil des Buches bildet ein ausf�hrlicher datenbasierter Vergleich zwischen MSA-Programmen, der als Entscheidungshilfe f�r die Programmauswahl f�r dein n�chstes Alignment dienen soll.

Theodor Sperlea studierte in Marburg Biologie und Molecular and Cellular Biology mit einem Schwerpunkt in Mikrobiologie und Genetik. Früh im Studium hatte er erste Kontaktmöglichkeiten mit MSAs als Werkzeug zur Untersuchung von evolutionären Verhältnissen zwischen Genen verschiedener Organismen. Durch seine Promotion, in der er die Ökologie von Mikroorganismen in Seen mit statistischen und bioinformatischen Methoden untersucht hat, konnte er sich einen tieferen Einblick in die informatische Seite und somit die Funktionsweise von MSA-Programmen erarbeiten.

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