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Neurodegenerazione da ferro by Khan, Mateen A.

Neurodegenerazione da ferro

by Mateen A. Khan
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Book cover type: Paperback
  • ISBN13: 9786200487490
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Edizioni Sapienza
  • Publisher Imprint: Edizioni Sapienza
  • Publication Date:
  • Pages: 224
  • Original Price: GBP 77.0
  • Language: Italian
  • Edition: N/A
  • Item Weight: 336 grams
  • BISAC Subject(s): Life Sciences / Biology

La ricerca sulla neurodegenerazione da ferro è cresciuta enormemente negli ultimi decenni e questi progressi sono stati documentati in numerosi articoli. Tuttavia, poche pubblicazioni si concentrano specificamente sul sovraccarico di ferro nel cervello e sulla sovraespressione della proteina precursore dell'amiloide di Alzheimer attraverso le vie di regolazione dell'Iron Responsive Element (IRE), nonostante le numerose raccolte che trattano argomenti relativi al metabolismo del ferro e alla malattia di Alzheimer. Decifrare i complessi meccanismi di aggregazione amiloide e le vie di segnalazione IRE è essenziale per comprendere i misteri della progressione dell'Alzheimer.Questo libro, Iron Neurodegeneration, spiega in dettaglio come viene regolato il metabolismo del ferro e come influisce sullo sviluppo delle malattie neurodegenerative. L'obiettivo principale è quello di esplorare il modo in cui gli aggregati amiloidi si trasformano nella traduzione dell'mRNA dell'IRE e di identificare potenziali bersagli terapeutici per le patologie neurodegenerative. Questo libro è destinato a un ampio pubblico: i professionisti esperti apprezzeranno le descrizioni e le discussioni approfondite, mentre gli studenti, i ricercatori e gli scienziati che si avvicinano per la prima volta all'argomento trarranno beneficio dall'introduzione completa che fornisce una solida base intellettuale.

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