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New epitome of human red blood cell destruction by Yoshiaki Sugawara

New epitome of human red blood cell destruction

by Yoshiaki Sugawara
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Book cover type: Paperback
  • ISBN13: 9783659531989
  • Binding: Paperback
  • Subject: N/A
  • Publisher: LAP Lambert Academic Publishing
  • Publisher Imprint: LAP Lambert Academic Publishing
  • Publication Date:
  • Pages: 100
  • Original Price: GBP 24.82
  • Language: English
  • Edition: N/A
  • Item Weight: 159 grams
  • BISAC Subject(s): Life Sciences / Biochemistry

Human erythrocytes survive in the circulation for about 120 days. How do they appreciate aging and determine their lifespan? The objective of this monograph is to present a fully new compendium (molecular-sensing) of Heinz body formation mechanisms inherent in human erythrocytes, whereby α1-β1 (and α2-β2) interface of the hemoglobin molecule (α2β2) controls removal of erythrocytes from the blood circulation by triggering degradation of the molecule to hemichrome, and subsequent clustering of Heinz bodies within the erythrocytes depending on the internal and extraneous conditions of the erythrocyte. So, Heinz body-containing red cells become trapped in the spleen and undergo hemolysis.

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