Nonhuman Primate Research in the Laboratory: Core Principles and Practical Considerations
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This comprehensive and yet succinct guide provides practical, hands-on guidance for conducting non-human primate (NHP) research with the highest standards of ethical care and scientific precision.
Drawing on an array of resources and decades of personal experience, this book covers everything from species-specific behaviours, appropriate housing and enrichment programs to detailed protocols for anaesthesia, analgesia, perioperative nursing and surgical procedures. Unlike existing works that often focus on exhaustive detail or are geared toward other species, this volume is concise and targeted, making it ideal for new and experienced scientists in basic and applied research.
The chapters offer fundamental information, step-by-step protocols, illustrative figures, definitions and further reading suggestions, allowing readers to navigate complex procedures with confidence. The book also addresses the unique ethical and technical challenges of invasive research on NHPs, a species invaluable to science for its genetic and physiological similarities to humans. From documentation practices to medication lists and environmental enrichment strategies, the present work provides the foundational knowledge and operational insights needed to ensure animal welfare and scientific integrity.
With this resource, readers gain a streamlined yet thorough reference that not only enhances research quality but also ensures that ethical considerations are met, making it an invaluable companion for anyone involved in NHP research, including expert personnel and veterinarians working with the animals.
Jennifer Smuda is a neuroscientist with a dedicated focus on animal welfare. She completed her Ph.D. in neuroscience at the University of Tuebingen, Germany, followed by a postdoctoral fellowship at the Max Planck Institute for Biological Cybernetics in Tuebingen, Germany. She subsequently joined the International Center for Primate Brain Research in Shanghai, China, where she played a key role in establishing and developing a state-of-the-art research facility. While her early research centred on the functional asymmetries of the macaque insular cortex, she now leads and manages the non-human primate facility, with a focus on the welfare of the animals in her care and the advancement of the wellbeing of non-human primates in research worldwide.
Nikos K. Logothetis is a renowned neuroscientist specialising in the neural mechanisms underlying visual perception and cognition. He earned his Ph.D. in neuroscience from the Ludwig Maximilian University in Munich, Germany. After a postdoctoral fellowship and subsequent research at MIT and Baylor College of Medicine, he became the director of the Department of Physiology of Cognitive Processes at the Max Planck Institute for Biological Cybernetics in Tuebingen, Germany. His pioneering research has significantly advanced our understanding of the relationship between neuronal activity and the BOLD signal in fMRI studies. Professor Logothetis currently serves as the director of the International Center for Primate Brain Research in Shanghai, China.
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