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Oncogene-Directed Therapies by Janusz W. Rak

Oncogene-Directed Therapies

by Janusz W. Rak
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Book cover type: Hardcover
  • ISBN13: 9780896039827
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Humana
  • Publisher Imprint: Humana
  • Publication Date:
  • Pages: 487
  • Original Price: USD 169.99
  • Language: English
  • Edition: 2003
  • Item Weight: 1212 grams
  • BISAC Subject(s): Oncology / General

Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.

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