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Organometallic Chemistry in Industry: A Practical Approach by Editor: Thomas J. Colacot, Editor: Carin C.C. Johansson Seechurn, Foreword by: Robert H. Grubbs (California Institute of Technology, Pasadena, USA)

Organometallic Chemistry in Industry: A Practical Approach

by Editor: Thomas J. Colacot , Editor: Carin C.C. Johansson Seechurn , Foreword by: Robert H. Grubbs (California Institute of Technology, Pasadena, USA)
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Hardcover: Hardcover
  • ISBN13: 9783527345175
  • Binding: Hardcover
  • Subject: N/A
  • Publisher: Wiley
  • Publisher Imprint: Wiley-VCH
  • Publication Date:
  • Pages: 336
  • Original Price: USD 121.95
  • Language: English
  • Edition: N/A
  • Item Weight: 800 grams
  • BISAC Subject(s): Chemistry / Organic

Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies

This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R&D researchers as well as Ph.D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions.

Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates. The book also examines aspects of homogeneous hydrogenation from industrial research; the latest industrial uses of olefin metathesis; and more.

-Includes rare industrial case studies difficult to find in current literature
-Helps readers successfully carry out their own reactions
-Covers topics like flow chemistry, cross-coupling reactions, and dehydrative decarbonylation
-Features a foreword by Nobel Laureate R. H. Grubbs
-A perfect resource for every R&D researcher in industry
-Useful for PhD students and postdocs: excellent preparation for a job interview

Organometallic Chemistry in Industry: A Practical Approach is an excellent resource for all chemists, including those working in the pharmaceutical industry and organometallics.

Thomas J. Colacot is R&D Fellow and Director of Global Technology Innovation (Lab and Specialty Chemicals) at Millipore Sigma, USA. His expertise is in the areas of new product and technology development, process R&D, scale-up- tech transfers of organic, organometallic, and fine chemicals relevant for pharmaceutical, electronic, and biological applications with very strong interactions/partnership with customers.

Carin C.C. Johansson Seechurn is Lead Scientist in Life Science Technologies division of Johnson Matthey in Cambridge, UK, where she is working on the development and scale-up of novel homogeneous metal catalysts.

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