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Peptide and Protein Drug Analysis by Ronald Reid

Peptide and Protein Drug Analysis

by Ronald Reid
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Book cover type: Paperback
  • ISBN13: 9780367399269
  • Binding: Paperback
  • Subject: N/A
  • Publisher: Taylor & Francis
  • Publisher Imprint: CRC Press
  • Publication Date:
  • Pages: 904
  • Original Price: GBP 67.99
  • Language: English
  • Edition: N/A
  • Item Weight: 1860 grams
  • BISAC Subject(s): Pharmacy, Biochemistry, and Pharmacology

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design.
Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication.
Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis

  • discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability
  • analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology
  • examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods
  • highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry
  • demonstrates uses of unnatural mutagenesis and combinatorial chemistry
  • explores mass spectrometry, protein sequence, and carbohydrate analysis
  • illustrates bioassays and other new functional analysis methods
  • surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR)
  • addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells
  • reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering
  • and more!
    Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemis

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